David Taylor, Ph.D.
Principal Investigator
David is an Associate Professor in the Department of Molecular Biosciences. He started as an Assistant Professor at UT Austin in September 2016. He earned his Ph.D. at Yale University and performed postdoctoral training at UC Berkeley with Eva Nogales and Jennifer Doudna. He has a passion for RNPs. He loves the Warriors, Syracuse basketball, teaching, and ‘starting’ projects that other lab members actually finish.


Helen Chen, Ph.D.
Research Associate and Lab Manager
Helen joined the lab as Research Associate/Lab manager in October 2016. She got her Ph.D. in Biochemistry at Texas A&M University with Dr. James Sacchettini. She enjoys gardening and cooking in addition to Science.
Kaoling Guan, Ph.D.
Postdoctoral Researcher
Kaoling joined the Taylor Lab as a postdoctoral researcher in April of 2023. He completed his Ph.D. at the University of Giessen, Germany at the end of 2022. During his Ph.D., he studied plant phytochrome structure and function by using X-ray crystallography and other biochemical approaches. In Taylor lab, Kaoling is interested in learning Cryo-EM and applying it to understand working mechanisms of novel biomacromolecular machines. Kaoling likes playing basketball in his free time.


Jacquelyn Wright
Graduate Student (Joint with Professor Daniel Dickinson)
Jacquelyn is a Biochemistry graduate student who joined the Taylor and Dickinson labs in the summer of 2021. Before UT, she earned a B.S. in Chemistry on the Biochemistry track with a second major in Spanish and Hispanic Studies at Creighton University in 2020. While working there in Dr. Lynne Dieckman’s lab, Jacquelyn developed a TIRF microscopy system to investigate an interaction of two proteins that functions in gene silencing. Her work at UT focuses on using fluorescent microscopy methods to better understand the biophysics and mechanisms of CRISPR-Cas systems. Outside of the lab, Jacquelyn loves exploring food around Austin and spending time outdoors with friends and her dog.
Matt Hooper
Graduate Student
Matt joined the Taylor Lab as a graduate student in January 2022. He earned a B.S. in Neuroscience with a certificate in Business from The University of Texas at Austin in 2019. After graduating, Matt spent 2 years working as a Research & Development scientist at the biotechnology company, PerkinElmer, before returning to UT. Currently, he is interested in understanding the structural and functional mechanisms of naturally occurring and engineered CRISPR-Cas systems. Outside of lab, Matt enjoys writing music, playing video games, and all forms of true crime media.


Zeyi (Joey) Yu
Graduate Student
Joey joined the Taylor Lab as a graduate student in January 2023. He earned a M.S. in Medicinal Chemistry from Sun Yat-sen University in 2022. There he studied specific secondary structures of nucleic acids G-quadruplexes by using fluorescent microscopy methods. Currently, he is interested in understanding the structural and functional mechanisms of novel CRISPR-Cas systems through cryo-EM. In his spare time, he loves playing ultimate frisbee, bouldering, and watching live music shows.
Rodrigo Fregoso Ocampo
Graduate Student
Rodrigo joined the Taylor Lab as a graduate student in January 2023. He earned his B.S. in Chemistry from UC Berkeley in 2020. After graduating, Rodrigo spent two years working on the characterization of novel CRISPR systems at Metagenomi Inc before moving to Austin to pursue a PhD. He is interested in obtaining structural and kinetic insights into the mechanisms of novel cas9 and cas12 systems. Outside of lab, Rodrigo enjoys watching a good football game, hiking, playing badminton, and going to a heavy metal concert every once in a while.


Nathan Appleby
Graduate Student
Nathan joined the Taylor Lab as a graduate student in January 2025. He earned his B.S. in Biochemistry from The University of Texas at Austin in 2024, where he studied the kinetics of Cas12a with novel guide constructs. His research interests include characterizing CRISPR-Cas systems using structural biology and kinetics. Outside the lab, Nathan enjoys playing chess and watching UT football games.
Carlos Arguello
Graduate Student
Carlos joined the Taylor lab as a graduate student in January 2025. He earned a B.S. in Biochemistry from the University of Texas at Austin in 2024. There, he studied and engineered retron reverse transcriptases in Ilya Finkelstein’s lab. Now, he is interested in determining the molecular mechanisms of novel bacterial immune systems through structural and kinetic methods. In his free time, he likes to see live music, watch movies, and lift weights.


Madeline West
Research Associate
Madeline joined the lab as a Research Associate in February 2025. She completed her B.S. in Biochemistry with a certificate in Pre-Health Professions at The University of Texas at Austin in 2024. Currently she is working on the design and kinetic characterization of novel gene editing tools. Outside of the lab, she enjoys going to the gym, watching anime, and cooking exotic dishes.
Adam Franco
Undergraduate Researcher
Adam joined the Taylor Lab in Spring 2023. He has a BSA in Biology with a minor in Healthcare Reform and Innovation. His focus is centered on the characterization of a DNA-binding protein. Outside the lab, he enjoys running, traveling, and watching sports. Adam has aspirations to attend medical school after graduation.


Ben Hoover
Undergraduate Researcher
Ben joined the Taylor Lab in Spring 2024. He is pursuing a BSA in Biology with a certificate in Core Texts and Ideas. His research focus in the lab is on an anti-phage protein with both helicase and nuclease activities. In his free time he enjoys weightlifting, playing video games, and watching F1. Ben hopes to attend medical school after graduating.
Amrutha Mummidi
Undergraduate Researcher
Amrutha joined the Taylor Lab in Fall 2024. She is a sophomore at UT Austin pursuing a major in Journalism and Health Reform & Innovation on the Pre-Medical track. Amrutha is passionate about the intersection of journalism and healthcare, and is dedicated to exploring how effective communication can drive positive change in the medical field. Outside the lab, she spends her time dancing, painting, or rewatching episodes of New Girl. A fun fact about Amrutha is that she has her own radio show! Amrutha has aspirations to attend medical school after graduation.Amrutha joined the Taylor Lab in Fall 2024. She is a sophomore at UT Austin pursuing a major in Journalism and Health Reform & Innovation on the Pre-Medical track. Amrutha is passionate about the intersection of journalism and healthcare, and is dedicated to exploring how effective communication can drive positive change in the medical field. Outside the lab, she spends her time dancing, painting, or rewatching episodes of New Girl. A fun fact about Amrutha is that she has her own radio show! Amrutha has aspirations to attend medical school after graduation.


Isabella Krudop
Undergraduate Researcher
Isabella joined the Taylor Lab in Fall 2024. She is pursuing a BS in Biochemistry at UT. Currently, her focus is centered on Cas12 systems. Outside the lab, she enjoys baking, hiking, and assembling jigsaw puzzles. Isabella has aspirations to pursue a PhD after graduation.
Susannah Lynn-Macrae
Beckman Scholar / Undergraduate Researcher
Susannah joined the Taylor Lab as a Beckman Scholar in May 2025. She is pursuing a BSA in Molecular, Cellular, and Developmental Biology and a minor in French at The University of Texas at Austin. Previously, she studied the genetics of neurodevelopmental disorders in the Golzio Lab at the Institute of Genetics, Molecular and Cellular Biology (IGBMC) in Strasbourg, France. Her current research focuses on the biochemical and structural characterization of CRISPR enzymes and other bacterial immunity effectors. Outside the lab, Susannah works as an EMT at music festivals, concerts, and sporting events around Austin and enjoys bouldering and running in her spare time.

Lab Alumni
Graduate Students
Matthew Schepers (2018-2020; M.S.): Currently Marketing Communications Manager at Danaher
Eric Verbeke (2017-2021; Ph. D.): Currently Postdoc at Princeton University
Evan Schwartz (2017-2022; Ph. D.): Currently support scientist at Sauer Structural Biology Laborotory
Catie McCafferty (2018-2022; Ph.D): Currently Postdoc at Biozentrum University of Basel, Switzerland
Roisin O’Brien (2018-2023; Ph.D.): Currently Analysist at Outcome Capital
Jamie Yelland (2018-2023; Ph.D.): Currently Postdoc at Fred Hutch Cancer Center
Grace Hibshman (2020-2025; Ph.D.): Currently Jane Coffin Childs Fellow at UC Berkeley
Postdoctoral Fellows
Shanzhong Gong (2016-2019)
Yi Zhou (2017-2019)
Mu-Sen Liu (2017-2021)
Zhongwu Zhou (2019-2021)
Isabel Strohkendl (2021-2024)
Jack Bravo (2020-2024)
Kaitlyn Kiernan (2023-2024)
Senior Scientist at Tango Therapeutics
Cryo-EM Lead, Regeneron
Senior Scientist at Tango Therapeutics
CryoEM Facility at UMass Medical School
Senior Scientist at Life Edit Therapeutics
Assistant Professor at Institute of Science and Technology Austria (ISTA)
Postdoc at Institute of Science and Technology Austria (ISTA)
Undergraduate Students
Anna Cruz (2017-2019; B.S.)
Kyungseok Jung (2017-2021; B.S.)
Delisa Ramos (2019 – 2023; B.S.)
Shashwat Limbasia (2022-2023)
Currently Technician at Microconsult, Inc.
Currently at Yale School of Medicine
Currently grad student at UCSD
Currently at UT Austin
